HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-phosphonobutanoate → Ethyl 2-ethyl-3-(4-methoxy-3-{2-oxo-2-[4-(trifluoromethyl)anilino]ethyl}phenyl)-2-propenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-phosphonobutanoate | HCID 21868151 | — |
| Reactant | N-[4-(trifluoromethyl)phenyl]-2-(5-formyl-2-methoxyphenyl)acetamide | HCID 22493985 | — |
| Product | Ethyl 2-ethyl-3-(4-methoxy-3-{2-oxo-2-[4-(trifluoromethyl)anilino]ethyl}phenyl)-2-propenoate | HCID 69800465 | 88.5% |
Reaction Steps
0.7 g of N-[4-(trifluoromethyl)phenyl]-2-(5-formyl-2-methoxyphenyl)acetamide and 1.6 g of ethyl 2-phosphonobutanoate were treated in the same manner as in Production Example 1a), to give 0.8 g of ethyl 2-ethyl-3-(4-methoxy-3-{2-oxo-2-[4-(trifluoromethyl)anilino]ethyl}phenyl)-2-propenoate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06884821B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-1e2eb6c06b7648c09aaeb99e3545c462 |
| Source note | uspto-grants-2005_04 |