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HRID 1816572作成日：2026年10月25日

2-Methoxy-4-(trifluoromethyl)benzoic acid → 2-Isopropoxy-3-[4-methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)phenyl]propanoic acid

https://huagongshe.com/reaction/1816572

反応式

関与物質

役割名称HCID仕込み量
反応物2-Methoxy-4-(trifluoromethyl)benzoic acidHCID 3690873—
反応物Ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoateHCID 22493983—
生成物2-Isopropoxy-3-[4-methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)phenyl]propanoic acidHCID 2249395362.9%

反応手順

0.15 g of ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate and 0.24 g of 2-methoxy-4-(trifluoromethyl)benzoic acid were treated in the same manners as in Example 19d) and then in Example 1d), to give 0.15 g of 2-isopropoxy-3-[4-methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)phenyl]propanoic acid as a pale yellow oil.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06884821B1
出典データセットuspto-grants-2005_04
ORD IDord-4e7a67575b6047ea9866f6d2800447bc
出典メモuspto-grants-2005_04