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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816587Generated: October 27, 2026

4-Chloro-2-fluorobenzoic acid → Ethyl 3-(3-{[(4-chloro-2-fluorobenzoyl)amino]methyl}-4-methoxyphenyl)-2-isopropoxypropanoate

https://huagongshe.com/reaction/1816587

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-fluorobenzoic acidHCID 99152—
ReactantEthyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoateHCID 22493983—
ProductEthyl 3-(3-{[(4-chloro-2-fluorobenzoyl)amino]methyl}-4-methoxyphenyl)-2-isopropoxypropanoateHCID 22494185—

Reaction Steps

Ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate and 4-chloro-2-fluorobenzoic acid were treated in the same manner as in Example 19d), to give ethyl 3-(3-{[(4-chloro-2-fluorobenzoyl)amino]methyl}-4-methoxyphenyl)-2-isopropoxypropanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884821B1
Source datasetuspto-grants-2005_04
ORD IDord-cad28325e8c042acb6418940dfd2b5d2
Source noteuspto-grants-2005_04