Ethylenediamine → HCID 22494176, compound

Participants

Reaction Steps

0.9 g of 2-ethyl-3-(4-methoxy-3-{2-oxo-2-[2,4-dichloroanilino]ethyl}phenyl)-2-propenoate was dissolved in 15 ml ethanol and 15 ml ethyl acetate, and 0.6 g of palladium-carbon poisoned with ethylene diamine was added. The reaction solution was stirred at room temperature for 5 hours in a hydrogen atmosphere, and then the palladium-carbon was filtered off, and the solvent was evaporated. The residue was purified by silica gel column chromatography, to give 0.44 g of ethyl 2-(4-methoxy-3-{2-oxo-2-[2,4-dichloroanilino]ethyl}benzyl)butanoate as a colorless oil.

Provenance & Evidence