Cuminol → HCID 22494067, compound

HRID 1816639Notes

Reaction equation

C([C:4]1[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][CH:5]=1)(C)C.Br[CH2:13][C:14]1[CH:15]=[C:16]([CH2:22][CH:23]([O:27][CH:28]([CH3:30])[CH3:29])[C:24]([O-:26])=[O:25])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]>>[CH:28]([O:27][CH:23]([CH2:22][C:16]1[CH:17]=[CH:18][C:19]([O:20][CH3:21])=[C:14]([CH2:13][O:9][CH2:8][C:7]2[CH:6]=[CH:5][C:4]([O:20][CH:19]([CH3:18])[CH3:14])=[CH:11][CH:10]=2)[CH:15]=1)[C:24]([OH:26])=[O:25])([CH3:30])[CH3:29]

Participants

Reactant 2

HCID 325Cuminol

HCID 224938933-[3-(Bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate

Product 1

HCID 22494067HCID 22494067, compound

Procedure

Using 4-isopropylbenzyl alcohol and 3-[3-(bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 2-isopropoxy-3-(3-[(4-isopropoxybenzyl)oxy]methyl-4-methoxyphenyl)propanoic acid was obtained in the same method as in Example 247).

Sources & evidence

ORD record: ord-32846cc5203542a18f71b6f24f7c5662
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884821B1

Reaction notes

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