(1,1'-Biphenyl)-4-carboxylic acid → HCID 22494095, compound

HRID 1816643Notes

Reaction equation

HRID 1816643 reaction equation
[C:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:16][CH2:17][C:18]1[CH:19]=[C:20]([CH2:26][CH:27]([O:33][CH:34]([CH3:36])[CH3:35])[C:28]([O:30]CC)=[O:29])[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]>>[CH:34]([O:33][CH:27]([CH2:26][C:20]1[CH:21]=[CH:22][C:23]([O:24][CH3:25])=[C:18]([CH2:17][NH:16][C:11](=[O:13])[C:10]2[CH:9]=[CH:8][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:15][CH:14]=2)[CH:19]=1)[C:28]([OH:30])=[O:29])([CH3:36])[CH3:35]

Participants

3

Reactant 2

HCID 66724(1,1'-Biphenyl)-4-carboxylic acidHCID 22493983Ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate

Product 1

HCID 22494095HCID 22494095, compound

Procedure

Using 4-phenylbenzoic acid and ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 2-isopropoxy-3-(4-methoxy-3-[(4-phenylbenzoyl)amino]methylphenyl)propanoic acid was obtained in the same method as in Example 19d) and then in Example 19e).

Sources & evidence

ORD record
ord-81ede2d0604a4dda87d95ef2cf74b31c
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Reaction notes

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