4-Cyclohexylbenzoic acid → HCID 22494257, compound

HRID 1816647Notes

Reaction equation

HRID 1816647 reaction equation
[CH:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=O)=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(OC([NH:23][CH2:24][C:25]1[CH:26]=[C:27]([CH2:33][CH:34]([O:40][CH:41]([CH3:43])[CH3:42])[C:35]([O:37]CC)=[O:36])[CH:28]=[CH:29][C:30]=1[O:31][CH3:32])=O)(C)(C)C>>[CH:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]([NH:23][CH2:24][C:25]3[CH:26]=[C:27]([CH2:33][CH:34]([O:40][CH:41]([CH3:43])[CH3:42])[C:35]([OH:37])=[O:36])[CH:28]=[CH:29][C:30]=3[O:31][CH3:32])=[O:13])=[CH:14][CH:15]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 883374-Cyclohexylbenzoic acidHCID 22493966HCID 22493966, compound

Product 1

HCID 22494257HCID 22494257, compound

Procedure

Using 4-cyclohexylbenzoic acid and ethyl 3-[3-([(tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl)-2-isopropoxypropanoate, 3-(3-[(4-cyclohexylbenzoyl)amino)methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid was obtained in the same method as in Example 38).

Sources & evidence

ORD record
ord-9a2c11e1714245d6b4c7361ed5f95944
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Reaction notes

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