2-Naphthoic acid → HCID 22494146, compound

HRID 1816648Notes

Reaction equation

HRID 1816648 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]([OH:13])=O.C(OC([NH:21][CH2:22][C:23]1[CH:24]=[C:25]([CH2:31][CH:32]([O:38][CH:39]([CH3:41])[CH3:40])[C:33]([O:35]CC)=[O:34])[CH:26]=[CH:27][C:28]=1[O:29][CH3:30])=O)(C)(C)C>>[CH:39]([O:38][CH:32]([CH2:31][C:25]1[CH:26]=[CH:27][C:28]([O:29][CH3:30])=[C:23]([CH2:22][NH:21][C:11]([C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)=[O:13])[CH:24]=1)[C:33]([OH:35])=[O:34])([CH3:41])[CH3:40]

Participants

3

Reactant 2

HCID 71232-Naphthoic acidHCID 22493966HCID 22493966, compound

Product 1

HCID 22494146HCID 22494146, compound

Procedure

Using 2-naphthalene carboxylic acid and ethyl 3-[3-([(tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 2-isopropoxy-3-(4-methoxy-3-[(2-naphthylcarbonyl)amino]methylphenyl]propanoic acid was obtained in the same method as in Example 38).

Sources & evidence

ORD record
ord-ba0ae6d2a9dc4da2a09fbe0e8cfb3b68
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Reaction notes

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