Bromocyclopentane → 2-Chloro-4-cyclopentyloxybenzoic acid

HRID 1816654Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[C:10]([OH:12])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].[CH:13]1(Br)[CH2:17][CH2:16][CH2:15][CH2:14]1>>[Cl:1][C:2]1[CH:11]=[C:10]([O:12][CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]

Participants

Reactant 2

HCID 8728Bromocyclopentane

HCID 134988302-Chloro-4-hydroxy-benzoic acid methyl ester

Product 1

HCID 224943402-Chloro-4-cyclopentyloxybenzoic acid

Procedure

Using methyl 2-chloro-4-hydroxybenzoate and cyclopentyl bromide, 2-chloro-4-cyclopentyloxybenzoic acid was obtained in the same manner as in Example 277b).

Sources & evidence

ORD record: ord-0bf1716407164b2e9e97f213b385c575
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884821B1

Reaction notes

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