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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816664Generated: October 25, 2026

3-(3-([(Tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate → 2-Isopropoxy-3-[4-methoxy-3-([2-propoxy-4-(trifluoromethyl)benzoyl]aminomethyl)phenyl]propanoic acid

https://huagongshe.com/reaction/1816664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-([(Tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoateHCID 22493954—
Reactant2-Propoxy-4-(trifluoromethyl)benzoic acidHCID 22494192—
Product2-Isopropoxy-3-[4-methoxy-3-([2-propoxy-4-(trifluoromethyl)benzoyl]aminomethyl)phenyl]propanoic acidHCID 22494042—

Reaction Steps

Using 2-propoxy-4-(trifluoromethyl)benzoic acid and 3-[3-([(tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 2-isopropoxy-3-[4-methoxy-3-([2-propoxy-4-(trifluoromethyl)benzoyl]aminomethyl)phenyl]propanoic acid was obtained in the same method as in Example 38).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884821B1
Source datasetuspto-grants-2005_04
ORD IDord-5b2ac76072d940c092952da2d8f39c33
Source noteuspto-grants-2005_04