3-Chloro[1,1'-biphenyl]-4-carboxylic acid → HCID 22493922, compound

HRID 1816668Notes

Reaction equation

HRID 1816668 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.C(OC([NH:24][CH2:25][C:26]1[CH:27]=[C:28]([CH2:34][CH:35]([O:41][CH:42]([CH3:44])[CH3:43])[C:36]([O:38]CC)=[O:37])[CH:29]=[CH:30][C:31]=1[O:32][CH3:33])=O)(C)(C)C>>[Cl:1][C:2]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=[CH:7][C:3]=1[C:4]([NH:24][CH2:25][C:26]1[CH:27]=[C:28]([CH2:34][CH:35]([O:41][CH:42]([CH3:44])[CH3:43])[C:36]([OH:38])=[O:37])[CH:29]=[CH:30][C:31]=1[O:32][CH3:33])=[O:6]

Participants

3

Reactant 2

HCID 214874263-Chloro[1,1'-biphenyl]-4-carboxylic acidHCID 22493966HCID 22493966, compound

Product 1

HCID 22493922HCID 22493922, compound

Procedure

Using 2-chloro-4-phenylbenzoic acid and ethyl 3-[3-([(tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 3-(3-[(2-chloro-4-phenylbenzoyl)amino]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid was obtained in the same method as in Example 38).

Sources & evidence

ORD record
ord-dea40705642e45969ce98fca82092fcc
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Reaction notes

Loading…