Tetrahydrofuran → HCID 22494657, compound

Participants

Reaction Steps

A mixture of methyl 4-(7-methoxy-n-heptyloxy)benzoate (1.5 g) and 1N-sodium hydroxide aqueous solution in ethanol (10 ml) and tetrahydrofuran (10 ml) was heated at 40-60° C. for 5 hours with stirring. The reaction mixture was concentrated under reduced pressure and water added to the residue and adjusted to pH 1 using hydrochloric acid. The precipitates were collected by filtration, washed with water and dried in vacuo to give 4-[7-methoxy-n-heptyloxy)benzoic acid (1.4 g) as a white solid.

Provenance & Evidence