HCID 22494617, compound → HCID 22494683, compound

Participants

Reaction Steps

A mixture of crude 1-acetyl-4-[4-[3-(2-cyclohexen-1-yloxy)propyloxy]phenyl]piperazine (1.55 g) in ethanol (16 ml) was hydrogenated at atmospheric pressure with 10% palladium-carbon (0.16 g) for 5 hours. After removal of catalyst by filtration, the filtrate was concentrated in vacuo to give crude 1-acetyl-4-[4-(3-cyclohexyloxypropyloxy)phenyl]piperazine (1.18 g), that was used in the next reaction directly, as a brown oil.

Provenance & Evidence