Benzamide → HCID 69370278, compound

HRID 1816805Notes

Reaction equation

[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]=[CH:11][C:12]3[C:20]4[C:15](=[CH:16][C:17]([N:21]([CH3:29])[C:22]5[CH:27]=[CH:26][CH:25]=[C:24]([NH2:28])[CH:23]=5)=[CH:18][CH:19]=4)[NH:14][N:13]=3)=[CH:9][C:4]=2[O:3][CH2:2]1.[C:30](N)(=[O:37])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]=[CH:11][C:12]3[C:20]4[C:15](=[CH:16][C:17]([N:21]([CH3:29])[C:22]5[CH:23]=[C:24]([NH:28][C:30](=[O:37])[C:31]6[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=6)[CH:25]=[CH:26][CH:27]=5)=[CH:18][CH:19]=4)[NH:14][N:13]=3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

Reactant 2

HCID 2331Benzamide

HCID 69370452HCID 69370452, compound

Product 1

HCID 69370278HCID 69370278, compound

Procedure

N-[3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-1H-indazol-6-yl]-N-methyl-benzene-1,3-diamine (prepared as described in Example 15) was converted to N-(3-{[32-benzo[1,3]dioxol-5-yl-vinyl)1H-indazol-6-yl]-methyl-amino}-phenyl)-benzamide in the manner described in Example 12(a). LCMS (ESI) [M+H]/z Calc'd 489, Found 489. Anal. Calc'd: C, 73.76; H, 4.95; N, 11.47. Found: C, 73.19; H, 5.09; N, 11.20.

Sources & evidence

ORD record: ord-ea4d0e09680a4bc697a60e4a739cf01c
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884890B2

Reaction notes

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