HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → N-[4-Bromo-2-(1-hydroxy-1-methyl-ethyl)-phenyl]-2-chloro-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 2-(2-Amino-5-bromophenyl)propan-2-ol | HCID 12042275 | — |
| Product | N-[4-Bromo-2-(1-hydroxy-1-methyl-ethyl)-phenyl]-2-chloro-acetamide | HCID 68864694 | — |
Reaction Steps
Prepared from 2-(2-amino-5-bromophenyl)propan-2-ol and chloro acetyl chloride generally according to the procedure described in example 1. An off-white solid: mp 133-134° C. 1H-NMR (DMSO-d6) δ 11.21 (s, 1H), 8.12 (d, J=8.6 Hz, 1H), 7.46 (dd, J=8.6, 2.3 Hz, 1H), 7.44 (d, J=2.3 Hz, 1H), 6.28 (s, 1H), 4.43 (s, 2H), 1.53 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598237B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-1c00fd48005142318f15caba8be7b47a |
| Source note | uspto-grants-2009_10 |