HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → 7-(3,5-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-thione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | 7-(3,5-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one | HCID 24956731 | — |
| Product | 7-(3,5-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-thione | HCID 24956732 | — |
Reaction Steps
Prepared from 7-(3,5-difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one and Lawesson's Reagent using the procedure of example 10. 1H-NMR (DMSO-d6) δ 12.01 (s, 1H), 7.70-7.63 (m, 2H), 7.59-7.48 (m, 2H), 7.41 (d, J=8.82 Hz, 1H), 7.28-7.18 (m, 1H), 4.51 (s, 2H), 1.62 (s, 6H); MS (FI) m/z 318 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598237B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-0bbf698768a44766b0988080e65b4f5c |
| Source note | uspto-grants-2009_10 |