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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817091Generated: October 27, 2026

Quinoxaline-2-carbaldehyde → 4-Quinoxalin-2-ylmethyl-piperazine-1-carboxylic acid phenylamide

https://huagongshe.com/reaction/1817091

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinoxaline-2-carbaldehydeHCID 594088—
ReactantN-phenylpiperazine-1-carboxamideHCID 7015289—
Product4-Quinoxalin-2-ylmethyl-piperazine-1-carboxylic acid phenylamideHCID 57880852—

Reaction Steps

The title compound was prepared from piperazine-1-carboxylic acid phenylamide and 2-quinoxaline-carboxaldehyde in analogy with Example 18. 1H NMR (400 MHz, CDCl3): 8.96 (s, 1H), 8.06-7.98 (m, 2H), 7.72-7.66 (m, 2H), 7.28-7.16 (m, 4H), 7.96-7.92 (m, 1H), 6.42 (s, 1H), 3.85 (s, 2H), 3.48-3.45 (m, 4H), 3.55-3.52 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598249B2
Source datasetuspto-grants-2009_10
ORD IDord-f67b7b0f681b4d77ad3528bc6f330027
Source noteuspto-grants-2009_10