Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817101Generated: October 29, 2026

4-Methylbenzaldehyde → 4-[(4-methylphenyl)methyl]-N-phenylpiperazine-1-carboxamide

https://huagongshe.com/reaction/1817101

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
ReactantN-phenylpiperazine-1-carboxamideHCID 7015289—
Product4-[(4-methylphenyl)methyl]-N-phenylpiperazine-1-carboxamideHCID 6469656—

Reaction Steps

The title compound was prepared from piperazine-1-carboxylic acid phenylamide and 4-methylbenzaldehyde. 1H NMR (400 MHz, CDCl3): 7.35-7.00 (m, 9H), 6.32 (s, 1H), 3.50-3.48 (m, 6H), 2.49-2.46 (m, 4H), 2.35 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598249B2
Source datasetuspto-grants-2009_10
ORD IDord-4605baab26ca4e44a823db6dd018ec53
Source noteuspto-grants-2009_10