Methyl 3-bromopropanoate → HCID 86598626, compound

HRID 1817144Notes

Reaction equation

HRID 1817144 reaction equation
C[O:2][C:3](=[O:7])[CH2:4][CH2:5]Br.[CH3:8][O:9][C:10]1[CH:54]=[C:53]([O:55][CH3:56])[CH:52]=[C:51]([O:57][CH3:58])[C:11]=1/[CH:12]=[CH:13]/[CH:14]([S:24]([CH:27](/[CH:37]=[CH:38]/[C:39]1[C:44]([O:45][CH3:46])=[CH:43][C:42]([O:47][CH3:48])=[CH:41][C:40]=1[O:49][CH3:50])[C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([NH2:36])[CH:29]=1)(=[O:26])=[O:25])[C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([NH2:23])[CH:16]=1>>[CH3:58][O:57][C:51]1[CH:52]=[C:53]([O:55][CH3:56])[CH:54]=[C:10]([O:9][CH3:8])[C:11]=1/[CH:12]=[CH:13]/[CH:14]([S:24]([CH:27](/[CH:37]=[CH:38]/[C:39]1[C:40]([O:49][CH3:50])=[CH:41][C:42]([O:47][CH3:48])=[CH:43][C:44]=1[O:45][CH3:46])[C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([NH:36][CH2:5][CH2:4][C:3]([OH:7])=[O:2])[CH:29]=1)(=[O:26])=[O:25])[C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([NH:23][CH2:5][CH2:4][C:3]([OH:2])=[O:7])[CH:16]=1

Participants

3

Reactant 2

HCID 76934Methyl 3-bromopropanoateHCID 67401517HCID 67401517, compound

Product 1

HCID 86598626HCID 86598626, compound

Procedure

A solution of methyl-3-bromopropionate(40 mmol) and (E)-2,4,6-trimethoxystyryl-3-amino-4-methoxybenzylsulfone (10 mmol) was reacted according to General Method B. The product obtained was purified by recrystallization from acetone. (m.p. 156-158° C.)

Workup

  1. customThe product obtained
  2. customwas purified by recrystallization from acetone

Sources & evidence

ORD record
ord-ee535d82b20c451bb7cdbe2c1bc98d89
Source dataset
uspto-grants-2009_10
Patent number
US07598232B2

Reaction notes

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