Potassium Carbonate → HCID 68863391, compound

Participants

Reaction Conditions

Reaction Steps

5-bromo-3-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)pyrazin-2-amine (0.020 g, 0.063 mmol) (made in example 2), 1-(tert-butoxycarbonyl)pyrrole-2-boronic acid (0.052 g, 0.25 mmol), Pd(PPh3)2Cl2 (0.004 g, 0.0057 mmol) and K2CO3 (0.050 g, 0.25 mmol) were combined in 0.5 mL of N,N-dimethylformamide and heated to 200° C. in the SmithSynthesizer microwave for 8 minutes. The reaction mixture was concentrated in vacuo and the residue purified by HPLC to give 0.0027 g of the title compound.

Provenance & Evidence