HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-hydroxy-5-(4-methoxyphenyl)pentanoate → Ethyl (2R)-2-hydroxy-5-(4-methoxyphenyl)pentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-hydroxy-5-(4-methoxyphenyl)pentanoate | HCID 16128914 | — |
| Reactant | (2R)-2-hydroxy-5-(4-methoxyphenyl)pentanoic acid | HCID 57880329 | — |
| Product | Ethyl (2R)-2-hydroxy-5-(4-methoxyphenyl)pentanoate | HCID 11644522 | — |
Reaction Steps
Using (2R)-2-hydroxy-5-(4-methoxyphenyl)pentanoic acid (80% e.e.), ethyl 2-hydroxy-5-(4-methoxyphenyl)pentanoate was quantitatively obtained (80% e.e.) by a process similar to the process described in Reference Example 27. The optical purity analysis conditions are as follows: Column: AD-H (Chiralcel, DAICEL Chemical Industries Ltd.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598240B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-cb280e62cf3047ee92220522c2c15ec8 |
| Source note | uspto-grants-2009_10 |