Benzene, (2-bromoethoxy)- → HCID 11691864, compound

HRID 1817215Notes

Reaction equation

HRID 1817215 reaction equation
[N:1]12[CH2:8][CH2:7][C:4]([C:9]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[C:10]#[N:11])([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[C:24]1([O:30][CH2:31][CH2:32][Br:33])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Br-:33].[C:10]([C:9]([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:4]12[CH2:5][CH2:6][N+:1]([CH2:32][CH2:31][O:30][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)([CH2:2][CH2:3]1)[CH2:8][CH2:7]2)#[N:11]

Participants

3

Reactant 2

HCID 68526Benzene, (2-bromoethoxy)-HCID 11716432HCID 11716432, compound

Product 1

HCID 11691864HCID 11691864, compoundYield 66%

Procedure

Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)acetonitrile (0.0499 g, 0.165 mmol) and 2-bromoethyl phenyl ether (0.0760 g, 0.378 mmol) in 2CH3CN/3CHCl3 (4.0 mL) were reacted to give the desired product (0.0548 g, 66.0%). EI-MS m/z 423(M+) Rt (2.20 min).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-6d8b340fc5f9419bb97618565d1254b8
Source dataset
uspto-grants-2009_10
Patent number
US07598267B2

Reaction notes

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