HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzimidazole → 6-(2-Methyl-1H-benzimidazol-1-yl)-N-[(1S)-1-phenylethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzimidazole | HCID 11984 | — |
| Reactant | 6-Chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 58717080 | — |
| Product | 6-(2-Methyl-1H-benzimidazol-1-yl)-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 10336690 | 11% |
Reaction Steps
In a procedure analogous to example 12, reaction of 6-chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine (120 mg, 0.51 mmol) and 2-methyl-benzimidazole (75 mg, 0.57 mmol) furnished the product (18 mg, 11%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598272B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-22c0fb13e838488e94fbeecdd5066c19 |
| Source note | uspto-grants-2009_10 |