HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 43389031, compound → 1-[6-{[(1S)-1-phenylethyl]amino}pyrazin-2-yl]-N-(2-hydroxyethyl)-1H-benzimidazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 43389031 | HCID 43389031 | — |
| Reactant | 6-Chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 58717080 | — |
| Product | 1-[6-{[(1S)-1-phenylethyl]amino}pyrazin-2-yl]-N-(2-hydroxyethyl)-1H-benzimidazole-5-carboxamide | HCID 9801233 | — |
Reaction Steps
In a procedure analogous to example 12, reaction of 6-chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine (91 mg, 0.39 mmol) and benzimidazole 5-carboxylic acid (2-hydroxyethyl)amide (88 mg, 0.43 mmol) furnished the product which was purified by column chromatography (22 mg, 14%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598272B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-0b714114b6ce499bba2c24114eb49b95 |
| Source note | uspto-grants-2009_10 |