HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 5-[(4-Methylpiperazin-1-yl)carbonyl]-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 5-Benzimidazolecarboxylic acid | HCID 459456 | — |
| Product | 5-[(4-Methylpiperazin-1-yl)carbonyl]-1H-benzimidazole | HCID 178481034 | 63% |
Reaction Steps
In a procedure analogous to example 20, reaction of benzimidazole-5-carboxylic acid (400 mg, 2.50 mmol) and N-methylpiperazine (550 mg, 5.0 mmol) furnished the product (380 mg, 63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598272B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-bf8e0abd309a4673a40fad204bb83e51 |
| Source note | uspto-grants-2009_10 |