HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzimidazole → 6-(1H-Benzimidazol-1-yl)-N-[(1S)-1-(4-methoxyphenyl)ethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzimidazole | HCID 5798 | — |
| Reactant | 6-Chloro-N-[(1S)-1-(4-methoxyphenyl)ethyl]pyrazin-2-amine | HCID 58717083 | — |
| Product | 6-(1H-Benzimidazol-1-yl)-N-[(1S)-1-(4-methoxyphenyl)ethyl]pyrazin-2-amine | HCID 9974853 | 41.3% |
Reaction Steps
In a procedure analogous to example 25, reaction of 6-chloro-N-[(1S)—1-(4-methoxyphenyl)ethyl]pyrazin-2-amine (105 mg, 0.40 mmol) and benzimidazole (52 mg, 0.44 mmol) furnished the product (57 mg, 41%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598272B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-30f4204a275e4e548c9f65b90654922b |
| Source note | uspto-grants-2009_10 |