HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817497Generated: October 30, 2026
[4-(benzyloxy)phenyl][1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]methanone → HCID 11494004, compound
https://huagongshe.com/reaction/1817497
Participants
| Role | Name | HCID | Charge |
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| Reactant | [4-(benzyloxy)phenyl][1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]methanone | HCID 69061008 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Cyclohexene ethanol | HCID 18676862 | — |
| Product | HCID 11494004 | HCID 11494004 | 98.2% |
Reaction Steps
A mixture of [4-(benzyloxy)phenyl][1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]methanone (0.17 g, 0.38 mmol) and 10% palladium on carbon (0.10 g) in 10 mL ethanol/cyclohexene (3:1, v/v) was heated at 70° C. for 0.5 hours. The catalyst was filtered (celite) and the filtrate concentrated in vacuo to give crude product. The residue was crystallized from Et2O/hexane to give 0.130 g of product as a white solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07598286B2 |
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| Source dataset | uspto-grants-2009_10 |
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| ORD ID | ord-adb193b8e35d4d2092b370899e3c5871 |
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| Source note | uspto-grants-2009_10 |
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