HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 10287853, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 10173705 | HCID 10173705 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 10287853 | HCID 10287853 | — |
Reaction Steps
The title compound was synthesized by hydrolyzing ethyl 2-ethoxy-3-{4-[(E)-3-(4-methylsulfonyloxyphenyl)-2-propenylamino]-phenyl}propionate obtained in example 11 (140 mg, 0.313 mmol) in methanol-water (2:1, 6 mL) using lithium hydroxide (17 mg, 0.407 mmol) following the same procedure as described in the Example 14 (40 mg, 30.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598293B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a8cc6e267a2443a7a609a0b8dddba214 |
| Source note | uspto-grants-2009_10 |