HCID 66839836, compound → HCID 66839865, compound

HRID 1817788Notes

Reaction equation

HRID 1817788 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][CH:7]=[C:8]2[C:13]=1[NH:12][C:11]([C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1)=[CH:10][C:9]2=[O:20])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][CH:7]=[C:8]2[C:13]=1[NH:12][C:11]([C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1)=[CH:10][C:9]2=[O:20]

Participants

4

Reactant 1

HCID 66839836HCID 66839836, compound

Product 1

HCID 66839865HCID 66839865, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

8-Nitro-2-(4-pyridinyl)4(1H)-quinolinone (KN-352) was hydrogenated using Pd/C in ethanol to afford the title compound: MS-ES m/e 238 (M+H).

Sources & evidence

ORD record
ord-56c638b472fa43f99eaab6f41db4b355
Source dataset
uspto-grants-2009_10
Patent number
US07598377B2

Reaction notes

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