HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-Chloro-7-phenyl-7,8-dihydro-6H-quinolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 7-Phenyl-7,8-dihydroquinoline-2,5(1H,6H)-dione | HCID 13572419 | — |
| Product | 2-Chloro-7-phenyl-7,8-dihydro-6H-quinolin-5-one | HCID 57883277 | — |
Reaction Steps
In analogy to (Shanazarov, A. K.; Kuzovkin, V. A.; Chistjakov, V. V.; Granik, V. G. Khim. Geterotsikl. Soedin. 1991, (1) 86-92) 7-phenyl-7,8-dihydro-1H,6H-quinoline-2,5-dione was treated with phosphoryl chloride (POCl3) to give after chromatographical separation the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598384B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a76050bb9002428a8b38d540bf919cb1 |
| Source note | uspto-grants-2009_10 |