Phenol → 2-Phenoxy-7-phenyl-7,8-dihydro-6H-quinolin-5-one hydrochloride

HRID 1817822Notes

Reaction equation

HRID 1817822 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][CH:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:5][C:4]=2[N:3]=1.[C:19]1([OH:25])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[ClH:1].[O:25]([C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][CH:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:5][C:4]=2[N:3]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 578832772-Chloro-7-phenyl-7,8-dihydro-6H-quinolin-5-one

Product 1

HCID 690384092-Phenoxy-7-phenyl-7,8-dihydro-6H-quinolin-5-one hydrochloride

Procedure

In analogy to the procedure described in Example 9, 2-chloro-7-phenyl-7,8-dihydro-6H-quinolin-5-one was treated with phenol to give the title compound as a colorless solid.

Sources & evidence

ORD record
ord-35be3c6d2d9d4bc79994c7af9b60958c
Source dataset
uspto-grants-2009_10
Patent number
US07598384B2

Reaction notes

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