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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817865Generated: October 27, 2026

1-Chloro-4-(ethylsulfonyl)-2-nitrobenzene → 4-(Ethylsulfonyl)-2-nitro-N-(tetrahydro-2H-pyran-4-ylmethyl)aniline

https://huagongshe.com/reaction/1817865

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-(ethylsulfonyl)-2-nitrobenzeneHCID 1515859—
Reactant4-AminomethyltetrahydropyranHCID 2773210—
Product4-(Ethylsulfonyl)-2-nitro-N-(tetrahydro-2H-pyran-4-ylmethyl)anilineHCID 68871749—

Reaction Steps

The title compound was prepared according to the procedure described in Step A of Example 5 from 1-chloro-4-(ethylsulfonyl)-2-nitrobenzene (Step C of Example 2) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-b09c22ac7255405d83a12026b2461a2c
Source noteuspto-grants-2009_10