HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-(ethanesulfonyl)-2-nitrobenzene → 1-({[4-(Ethylsulfonyl)-2-nitrophenyl]amino}methyl)cyclopentanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-(ethanesulfonyl)-2-nitrobenzene | HCID 1515859 | — |
| Reactant | 1-(Aminomethyl)cyclopentan-1-ol--hydrogen chloride (1/1) | HCID 21109693 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 1-({[4-(Ethylsulfonyl)-2-nitrophenyl]amino}methyl)cyclopentanol | HCID 68870904 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Step A of Example 5 from 1-chloro-4-(ethylsulfonyl)-2-nitrobenzene (Step C of Example 2), 1-(aminomethyl)cyclopentanol hydrochloride (J. Med. Chem. 1981, 24, 12-16) and triethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598393B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-4d6e73a7a8f24101adf2d6fc9fd8975c |
| Source note | uspto-grants-2009_10 |