4-Aminomethyltetrahydropyran → HCID 68871306, compound

HRID 1817873Notes

Reaction equation

HRID 1817873 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([S:11]([CH2:14][CH3:15])(=[O:13])=[O:12])=[CH:4][N:3]=1.[NH2:16][CH2:17][CH:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1>>[CH2:14]([S:11]([C:5]1[CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]([NH:16][CH2:17][CH:18]2[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)=[N:3][CH:4]=1)(=[O:13])=[O:12])[CH3:15]

Participants

3

Reactant 2

HCID 27732104-AminomethyltetrahydropyranHCID 86241971HCID 86241971, compound

Product 1

HCID 68871306HCID 68871306, compound

Procedure

The title compound was prepared according to the procedure described in Step A of Example 5 from 2-chloro-5-(ethylsulfonyl)-3-nitropyridine (Step D) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).

Sources & evidence

ORD record
ord-319216d55f4e451ead5cd8d9588efdcd
Source dataset
uspto-grants-2009_10
Patent number
US07598393B2

Reaction notes

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