Methyl 4-chloro-3-nitrobenzoate → HCID 57636250, compound
Reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[NH2:15][CH2:16][CH:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[N+:12]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:2]=1[NH:15][CH2:16][CH:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)[C:6]([O:8][CH3:9])=[O:7])([O-:14])=[O:13]Participants
3
Procedure
The title compound was prepared according to the procedure described in Step A of Example 5 from methyl 4-chloro-3-nitrobenzoate (Lancaster Synthesis Ltd.) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).
Sources & evidence
- ORD record
- ord-3695669df4a340f1a987192d6a533525
- Source dataset
- uspto-grants-2009_10
- Patent number
- US07598393B2
Reaction notes
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