4-Bromo-1-fluoro-2-nitrobenzene → HCID 62386169, compound

HRID 1817896Notes

Reaction equation

HRID 1817896 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](F)=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[NH2:12][CH2:13][CH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:12][CH2:13][CH:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1

Participants

3

Reactant 2

HCID 27363284-Bromo-1-fluoro-2-nitrobenzeneHCID 27732104-Aminomethyltetrahydropyran

Product 1

HCID 62386169HCID 62386169, compound

Procedure

The title compound was prepared according to the procedure described in Step A of Example 5 from 4-bromo-1-flouro-2-nitrobenzene (Wako Pure Chemical Industries, Ltd.) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).

Sources & evidence

ORD record
ord-91b491cfac3e4387be94ea5c3b532475
Source dataset
uspto-grants-2009_10
Patent number
US07598393B2

Reaction notes

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