HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → (3R,5R)-3,5-Bis[(tert-butyldimethylsilyl)oxy]4-methylenecyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Aluminum isopropoxide | HCID 11143 | — |
| Reactant | HCID 10248733 | HCID 10248733 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (3R,5R)-3,5-Bis[(tert-butyldimethylsilyl)oxy]4-methylenecyclohexanone | HCID 10690562 | — |
Reaction Steps
For example, a solution of (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-4-methylenecyclohexanol (compound 9) in toluene is made to react with aluminum isopropoxide and cyclohexanone to produce (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-4-methylenecyclohexanone (compound 10).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598408B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-c6a0283300f74d42ba0635c2f00ef0f5 |
| Source note | uspto-grants-2009_10 |