HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-1-Aminoindan → 6-Bromo-2,3-dihydro-1H-inden-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 1-Indanone, 6-bromo- | HCID 139778 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Product | 6-Bromo-2,3-dihydro-1H-inden-1-amine | HCID 16244315 | — |
Reaction Steps
The title indanamine was generated from 6-bromo-1-indanone (2.00 g, 9.50 mmol), NaBH3CN (4.20 g, 66.84 mmol) and NH4OAc (22.00 g, 0.29 mol) according to the protocols as outlined in general procedure C. Spectroscopic data: 1H NMR (300 MHz, CDCl3) δ 1.59-1.73 (m, 3H), 2.44-2.56 (m, 1H), 2.70-2.82 (m, 1H), 2.84-2.98 (m, 1H), 4.29-4.40 (m, 1H), 6.98-7.18 (m, 1H), 7.26-7.38 (m, 1H), 7.4 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598417B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a2d6d335a1a34e219bcdce2db16a5ee3 |
| Source note | uspto-grants-2009_10 |