Hydrochloric Acid → (E,E)-2-(3,4-Dimethoxybenzylaminocarbonyl)-3-(3,4-dihydroxystyryl)acrylonitrile

関与物質

反応手順

To 3,4-dihydroxycinnamaldehyde (32 mg, 0.2 mmol) and N-(cyanoacetyl)3,4-dimethoxybenzylamide (47 mg, 0.2 mmol) in 8 mL of ethanol 40 μl of piperidine was added and the mixture was kept at room temperature for 1 h. 2N HCl and water were added and the precipitated solid was recrystallized from ethanol-water to give 52 mg (68%) of an orange solid. The product gave the following analytical data:

情報源と証拠