Hydrochloric Acid → HCID 69065255, compound

Participants

Reaction Steps

6-Acetylamino-N-benzylnaphthalene-1-sulfonamide (compound No. 7-1; 188 mg, 0.530 mmol) was suspended to a mixed solvent of 1-propanol (3.0 ml) and water (1.5 ml). Concentrated hydrochloric acid (1.5 ml) was added to the suspension and the mixture was refluxed for 1 hour. After cooling to room temperature, the separated crystal was collected and washed with 1-propanol and isopropyl ether to give the title compound as a light yellow crystal (118 mg, 63.8%).

Provenance & Evidence