5-nitronaphthalene-1-carboxylic acid → HCID 69058832, compound

HRID 1818070Notes

Reaction equation

HRID 1818070 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]([OH:16])=O)([O-:3])=[O:2].[C:17]([C:21]1[CH:28]=[CH:27][C:24]([CH2:25][NH2:26])=[CH:23][CH:22]=1)([CH3:20])([CH3:19])[CH3:18]>>[C:17]([C:21]1[CH:22]=[CH:23][C:24]([CH2:25][NH:26][C:14]([C:9]2[C:10]3[C:5](=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][CH:11]=3)[CH:6]=[CH:7][CH:8]=2)=[O:16])=[CH:27][CH:28]=1)([CH3:20])([CH3:18])[CH3:19]

Participants

3

Reactant 2

HCID 4589625-nitronaphthalene-1-carboxylic acidHCID 27356554-tert-Butylbenzylamine

Product 1

HCID 69058832HCID 69058832, compoundYield 42.6%

Procedure

Using 5-nitronaphthalene-1-carboxylic acid (197 mg, 0.907 mmol) and 4-tert-butylbenzylamine (107 mg, 0.998 mmol), the same operation as the Example 104(2) gave the title compound as a light yellow solid (140 mg, 42.6%).

Sources & evidence

ORD record
ord-ee55b41ad8c94e4099845c0eef524220
Source dataset
uspto-grants-2009_10
Patent number
US07598418B2

Reaction notes

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