2,3-Dimethoxybenzylamine → HCID 69057382, compound

HRID 1818071Notes

Reaction equation

HRID 1818071 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]([OH:16])=O)([O-:3])=[O:2].[CH3:17][O:18][C:19]1[C:26]([O:27][CH3:28])=[CH:25][CH:24]=[CH:23][C:20]=1[CH2:21][NH2:22]>>[CH3:17][O:18][C:19]1[C:26]([O:27][CH3:28])=[CH:25][CH:24]=[CH:23][C:20]=1[CH2:21][NH:22][C:14]([C:9]1[C:10]2[C:5](=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1)=[O:16]

Participants

3

Reactant 2

HCID 781062,3-DimethoxybenzylamineHCID 4589625-nitronaphthalene-1-carboxylic acid

Product 1

HCID 69057382HCID 69057382, compoundYield 55.1%

Procedure

Using 5-nitronaphthalene-1-carboxylic acid (250 mg, 1.15 mmol) and 2,3-dimethoxybenzylamine (0.18 ml, 1.20 mmol), the same operation as the Example 104(2) gave the title compound as a gray white solid (232 mg, 55.0%).

Sources & evidence

ORD record
ord-ae147fabf6ff4620987a91e82deb6f2f
Source dataset
uspto-grants-2009_10
Patent number
US07598418B2

Reaction notes

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