Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylboronic Acid → 2-ethyl-1-isobutyl-8-phenyl-1H-imidazo[4,5-c]quinolin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylboronic Acid | HCID 66827 | — |
| 반응물 | 8-Bromo-2-ethyl-1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 21984300 | — |
| 생성물 | 2-ethyl-1-isobutyl-8-phenyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 21984048 | — |
반응 단계
8-Bromo-2-ethyl-1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine and benzeneboronic acid were coupled according to the general procedure described in Part J of Example 1. Chromatography on silica gel (5%-7% methanol in CH2Cl2 gradient) afforded 2-ethyl-1-isobutyl-8-phenyl-1H-imidazo[4,5-c]quinolin-4-amine as a white solid, m.p. 233-235° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07598382B2 |
| 출처 데이터셋 | uspto-grants-2009_10 |
| ORD ID | ord-2f4aaa61083446d58395f6cca8361072 |
| 출처 메모 | uspto-grants-2009_10 |