HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Aminopropyl)-2-pyrrolidinone → 1-[3-(3-Nitro-7-phenylquinolin-4-ylamino)propyl]pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Aminopropyl)-2-pyrrolidinone | HCID 82111 | — |
| Reactant | 4-Chloro-3-nitro-7-phenylquinoline | HCID 21984335 | — |
| Product | 1-[3-(3-Nitro-7-phenylquinolin-4-ylamino)propyl]pyrrolidin-2-one | HCID 21984079 | 88.1% |
Reaction Steps
4-Chloro-3-nitro-7-phenylquinoline (3.51 g, 12.3 mmol) was treated with 1-(3-aminopropyl)pyrrolidin-2-one (2.3 mL, 16 mmol) according to the method described in Part E of Example 1 to provide 4.23 g of 1-[3-(3-nitro-7-phenylquinolin-4-ylamino)propyl]pyrrolidin-2-one as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598382B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-7e5aa140798847a2b105e14299930dad |
| Source note | uspto-grants-2009_10 |