HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → 1-(2-methylpropyl)-9-phenyl-1H-imidazo[4,5-c]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 9-bromo-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline | HCID 21984348 | — |
| Product | 1-(2-methylpropyl)-9-phenyl-1H-imidazo[4,5-c]quinoline | HCID 21984188 | — |
Reaction Steps
9-Bromo-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (0.34 mmol) and benzene boronic acid (62 mg, 0.51 mmol) were coupled according to Part J of Example 1. The work-up procedure described in Parts 125-135 was followed. The crude product was purified by HPFC (eluting with chloroform:CMA in a gradient from 100:0 to 85:15) to provide 1-(2-methylpropyl)-9-phenyl-1H-imidazo[4,5-c]quinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598382B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-83c7efc2660d4153a1681accbdc38a6d |
| Source note | uspto-grants-2009_10 |