HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[2-(4-amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-ethyl]methanesulfonamide → n-[2-(4-Amino-2-butyl-7-vinyl-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[2-(4-amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-ethyl]methanesulfonamide | HCID 21984323 | — |
| Reactant | Potassium vinyltrifluoroborate | HCID 23679353 | — |
| Product | n-[2-(4-Amino-2-butyl-7-vinyl-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide | HCID 21984133 | — |
Reaction Steps
N-[2-(4-Amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide was coupled with potassium vinyltrifluoroborate according to the procedure described in Part D of Examples 440-455 and recrystallized from acetonitrile to provide N-[2-(4-amino-2-butyl-7-vinyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598382B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-0f00b76aaac14233855695185a29dd7b |
| Source note | uspto-grants-2009_10 |