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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1818271Generated: October 25, 2026

n-Cyclopentylcyclohexanamine → [5-(3-Cyclohexyl-3-cyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid

https://huagongshe.com/reaction/1818271

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-CyclopentylcyclohexanamineHCID 219797—
ReactantEthyl 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetateHCID 351912—
Reactant[5-(3-Cyclohexyl-3-cyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid ethyl esterHCID 66872747—
Product[5-(3-Cyclohexyl-3-cyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acidHCID 57883528—

Reaction Steps

[5-(3-Cyclohexyl-3-cyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid ethyl ester prepared as described in general procedures (A) and (B) using cyclohexyl-cyclopentyl-amine and ethyl-2-[5-amino-1,3,4-thiadiazol-2-yl-thio]acetate. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598391B2
Source datasetuspto-grants-2009_10
ORD IDord-13fd4867a2cc4b1faacd09ef89947b73
Source noteuspto-grants-2009_10