Dimethylamine → 5-[[4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[5,4-g]isoquinolin-6-yl]sulfonyl]-N,N-dimethylpyridin-2-amine

HRID 181828Notes

Reaction equation

HRID 181828 reaction equation
[CH3:35][NH:36][CH3:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][C:13]3([CH2:31][O:32][CH2:33][CH3:34])[CH2:14][c:15]4[c:16]([n:21](-[c:24]5[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]5)[n:22][cH:23]4)[CH:17]=[C:18]3[CH2:19][CH2:20]2)[cH:6][n:7]1>>[c:2]1([N:36]([CH3:35])[CH3:37])[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][C:13]3([CH2:31][O:32][CH2:33][CH3:34])[CH2:14][c:15]4[c:16]([n:21](-[c:24]5[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]5)[n:22][cH:23]4)[CH:17]=[C:18]3[CH2:19][CH2:20]2)[cH:6][n:7]1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 871481436-[(6-Chloro-3-pyridinyl)sulfonyl]-4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[5,4-g]isoquinoline

Product 1

HCID 681947565-[[4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[5,4-g]isoquinolin-6-yl]sulfonyl]-N,N-dimethylpyridin-2-amine

Sources & evidence

ORD record
ord-958484c1ed8043bf99351e339857b6da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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