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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1818312Generated: October 31, 2026

1-(2-Chloroethyl)pyrrolidine → 1,1-Dicyclohexyl-3-[5-(2-pyrrolidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

https://huagongshe.com/reaction/1818312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)pyrrolidineHCID 81669—
ReactantDithioerythritolHCID 439352—
Reactant1,1-Dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-ureaHCID 86611192—
Product1,1-Dicyclohexyl-3-[5-(2-pyrrolidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-ureaHCID 57883476—

Reaction Steps

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 1-(2-chloroethyl)-pyrrolidine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598391B2
Source datasetuspto-grants-2009_10
ORD IDord-bfa8b45041934c2c926246cdba3ca9fd
Source noteuspto-grants-2009_10