HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 57883545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | p-Aminophenylacetic acid ethyl ester | HCID 225219 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1,1-Dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea | HCID 57883471 | — |
| Product | HCID 57883545 | HCID 57883545 | 30% |
Reaction Steps
Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (100 mg. 0.298 mmol), acetic acid (17 μL, 0.29 mmol), (4-amino-phenyl)-acetic acid ethyl ester (14 mg, 0.45 mmol) and sodium triacetoxyborohydride (101 mg, 0.48 mmol) to afford 43 mg (30%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598391B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-61a69919541f49bda8e52e56cb5df9e0 |
| Source note | uspto-grants-2009_10 |